S2147

Sigma

 

Monoclonal Anti-Superoxide Dismutase (SOD) antibody produced in mouse

clone SD-G6, ascites fluid

MDL number:MFCD00164740

Description

Immunogenrecombinant human copper-zinc superoxide dismutase (Cu-Zn-SOD).
SpecificityThe antibody recognizes natural and recombinant human-Cu-Zn-SOD, human placental SOD, and human erythrocyte SOD using direct capture or competitive ELISA. Cross-reactivity has been observed with human liver and salivary gland, rat salivary gland, pheochromocytoma cell line (PC12), and dog salivary gland. No reactivity was observed with SOD from bovine erythrocytes, kidney, and liver; dog erythrocytes; Bacillus stearothermophilus; E. coli, or horseradish.

Properties

antibody formascites fluid
cloneSD-G6 (monoclonal)
contains15 mM sodium azide
species reactivityhuman, rat, canine
application(s)indirect ELISA: 1:300
isotypeIgG1
Gene Informationhuman ... SOD1(6647)
 rat ... Sod1(24786)
shipped indry ice
storage temp.−20°C

Safety

WGK Germany3

Related Products

Related productS4946, Anti-Superoxide Dismutase (EC-SOD) antibody produced in rabbit

References

referenceCarrasco, J., et al., Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures. J. Neurosci. Res. 79, 522-534, (2005) Abstract
 Johnston, J.A., et al., Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis Proc. Natl. Acad. Sci. U. S. A. 97, 12571-12576, (2000) Abstract